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Real-world analysis of a drug combination for malignant peritoneal mesothelioma

A recent phase II study used real-world evidence to assess responses to a combination treatment of atezolizumab and bevacizumab in […]

Statins and COVID-19 outcomes

By analysing a large, diverse population, researchers at the University of San Diego School of Medicine showed that patients using […]

New diagnostic tool for Alzheimer’s could improve drug trial recruitment

Researchers at Lund University in Sweden have developed an algorithm that combines data from simple blood tests and brief memory […]

Meta-analysis of transcriptomic data from Huntington’s disease patients

Description of transcriptomic alterations in Huntington’s disease is essential for the identification of targets for biomedical studies and drug development. […]

Estimating IBD Treatment Effectiveness Using Electronic Health Records

Electronic health records (EHRs) are receiving growing attention as a potential source of real-world data. However, their suitability for evaluating […]

Reducing False Positive Drug Target Predictions

Target prediction with machine learning algorithms can help accelerate the identification of protein targets of hit molecules, limiting the number […]

Surrogate Endpoint Evaluation Methodology

Robust identification of clinical trial surrogate end points can help to accelerate the development of pharmacotherapies for diseases that are […]

AlzGPS: A Genome-Wide Positioning Systems Platform for Alzheimer’s Drug Discovery

Recent DNA/RNA sequencing and other multi-omics technologies have advanced our understanding of the biology and pathophysiology of Alzheimer’s disease. However, […]

IBDREAM Registry – Adverse Drug Reactions from Real-World Data in IBD

A recent study, published in Drug Safety, aimed to describe the adverse drug reactions reported in inflammatory bowel disease patients […]

The Promise of AI for Drug-Induced Liver Injury Prediction

Drug-induced liver injury is a common reason for the withdrawal of a drug from the market. Therefore, early assessment of […]