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Meta-analysis of transcriptomic data from Huntington’s disease patients

Description of transcriptomic alterations in Huntington’s disease is essential for the identification of targets for biomedical studies and drug development. […]

The dilemmas of using patient health data in research

The use of routine patient data in the form of administrative databases, electronic health records, and clinical registries in biomedical […]

Early clinical trial data supports amivantamab against a rare lung cancer mutation

Lung cancer is one of the leading causes of cancer death among men and women in the US. One option […]

Real-world analysis of the effects of inotropic agents on sepsis patients

In a recent big-data, real-world study, researchers demonstrated that hospital mortality is not significantly different between septic patients treated with […]

Data-driven eligibility criteria may make clinical trials more inclusive

Researchers have shown that relaxing the eligibility criteria of clinical trials in a data-driven manner can significantly increase the number […]

Interoperability: A three-pillar strategy to integrate health data

The Swiss Personalised Health Network developed a flexible, pragmatic framework that promotes interoperability between diverse biomedical datasets. The proposed three-pillar […]

The role of artificial intelligence (AI) and big data in drug discovery

For the first time, a review explored in depth how big data and artificial intelligence (AI) techniques are currently being […]

Are ‘virtual patients’ the future of clinical trials?

Researchers have demonstrated that an in-silico approach, using virtual patient data, was able to replicate clinical trial results and investigate […]

Artificial intelligence can identify the most effective targeted therapies for cancer patients

An artificial intelligence-based model has been used to match molecularly targeted agents (MTAs) to individual molecular tumour profiles, in the […]

A novel computer system can help inform future therapies for patients with inherited cardiovascular disease

Researchers from around the world have collaborated to develop a genomic computer system to show how some genetic mutations can […]