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Multi-omics analysis reveals acute myeloid leukemia metabolic variation mechanisms

Researchers at Kumamoto University have demonstrated that lysine-specific demethylase 1 (LSD1) shapes the variation in metabolic phenotypes seen in distinct […]

Could Translational Precision Medicine be the modern approach to drug discovery and development?

A recent study has explored the concept of a modern and collaborative approach to data-driven drug development called Translational Precision […]

AlzGPS: A Genome-Wide Positioning Systems Platform for Alzheimer’s Drug Discovery

Recent DNA/RNA sequencing and other multi-omics technologies have advanced our understanding of the biology and pathophysiology of Alzheimer’s disease. However, […]

Genomics in Drug Discovery & Development

Despite an increase in investment into R&D from biopharma companies, only 5-10% of drugs that enter early-stage clinical trials ever […]

Predicting Metabolite-Target Interactions for Drug Discovery

A recent article, published in Communications Biology, has outlined a method for expanding our understanding of host-microbiome interactions that will […]

How to integrate multi-omic data

With the advent of high-throughput techniques, we have a greater capability than ever before to study a diverse range of […]

Deep learning model estimates gene expression from DNA methylation and copy number variation

Genetic and epigenetic changes underpin the development of a plethora of biological conditions that can be acquired over the course […]

Varenka Rodriguez DiBlasi, Boehringer Ingelheim: Computational biology approaches towards interrogating the tumor microenvironment

Varenka Rodriguez DiBlasi, Exploratory Bioinformatics Lab Head of Cancer Immunology at Boehringer Ingelheim, shared a case study at D4 USA […]

D4 Europe 2020

D4 Europe is packed with case studies, evidence and intelligence that you can take back to your organisation and impact […]