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New database of transcriptional regulators for cancer drug development

Researchers from the University of Virginia School of Medicine have developed a new database of transcriptional regulators, which will help […]

DrugSpaceX: A Database of Drug-Like Chemicals

One of the most prominent topics in drug discovery is the efficient exploration of the vast number of drug-like chemicals […]

DrugCentral2021 – A Database for Drug Discovery and Repositioning

A recent study has described the new DrugCentral2021 database, which is a public resource that serves the scientific community by […]

Marine Natural Products Database for Drug Discovery

Marine organisms are expected to be an important source of inspiration for drug discovery. At present, very few databases exist […]

LEGEND: Large-scale Evidence Generation and Evaluation across a Network of Databases

The Observational Health Data Sciences and Informatics (OHDSI) international collaborative have launched a research initiative known as LEGEND. The aim […]

scREAD: single-cell RNA-Seq database for Alzheimer’s Disease

Researchers at The Ohio State University have developed an integrated database known as scREAD – single-cell RNA-Seq database for Alzheimer’s Disease. Alzheimer’s […]

A new workflow for drug discovery bypasses current inefficiencies

Researchers from the Laboratory of Computational Systems Biotechnology at EPFL, Switzerland, have developed a database – NICEdrug.ch – that could […]

Real-world analysis of the effects of inotropic agents on sepsis patients

In a recent big-data, real-world study, researchers demonstrated that hospital mortality is not significantly different between septic patients treated with […]

Data-driven eligibility criteria may make clinical trials more inclusive

Researchers have shown that relaxing the eligibility criteria of clinical trials in a data-driven manner can significantly increase the number […]

Data-driven approach to identify PROTAC targets

Proteolysis-targeting chimeras (PROTACs) are an emerging class of drugs that may offer new opportunities to overcome limitations associated with small-molecule […]