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Real-world analysis of the effects of inotropic agents on sepsis patients

In a recent big-data, real-world study, researchers demonstrated that hospital mortality is not significantly different between septic patients treated with […]

Data-driven eligibility criteria may make clinical trials more inclusive

Researchers have shown that relaxing the eligibility criteria of clinical trials in a data-driven manner can significantly increase the number […]

Predicting the success of COVID-19 clinical trials

Using machine learning algorithms and ensemble learning, researchers have modelled the factors underlying the completion or cessation of COVID-19 clinical […]

Real-world analysis of a drug combination for malignant peritoneal mesothelioma

A recent phase II study used real-world evidence to assess responses to a combination treatment of atezolizumab and bevacizumab in […]

Facilitating Remote Clinical Trials – A Review

Following the COVID-19 outbreak, which caused unprecedented disruption to the running of clinical trials, there has been an increasing interest […]

Data-driven eligibility criteria for COVID-19 clinical trials

We summarise a recent article, published in Journal of the American Medical Informatics Association, that evaluated the impact of eligibility […]

Virtual Clinical Trials

With the ongoing COVID-19 pandemic, virtual has become the new normal. From online lockdown quizzes to virtual events, communication through […]

Guidelines for clinical trials with an AI component

Here we summarise the CONSORT-AI and SPIRIT-AI extensions – guidelines for clinical trial protocols for interventions involving artificial intelligence (AI). […]

A framework to generate real-world evidence using real-world data from clinical notes

A new study, published as a preprint in BMC Medical Informatics and Decision Making, has described a framework to generate […]

Promises and pitfalls of precision medicine clinical trials, now and in the future

Availiable on demand here As we move towards an ever more personalised healthcare system, genomics is at the heart of […]